Title of article
A concise total synthesis of (+)-pyrenolide D
Author/Authors
Zhang، نويسنده , , Chaoli and Liu، نويسنده , , Jun and Du، نويسنده , , Yuguo، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2013
Pages
3
From page
3278
To page
3280
Abstract
The concise total synthesis of antitumor natural product (+)-pyrenolide D has been achieved in seven steps from readily available natural carbohydrate d-xylose with 10.8% overall yield. The key steps involved methylpropiolate-mediated stereoselective alkynylation on lactone carbonyl group and the tandem one-pot desilylation–spirolactonization.
Keywords
Pyrenolide D , hemiketal , natural product , xylose , Spiroketalization
Journal title
Tetrahedron Letters
Serial Year
2013
Journal title
Tetrahedron Letters
Record number
1884732
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