Title of article
A simple two-step access to diversely substituted imidazo[4,5-b]pyridines and benzimidazoles from readily available 2-imidazolines
Author/Authors
Mujumdar، نويسنده , , Prashant and Grkovic، نويسنده , , Tanja and Krasavin، نويسنده , , Mikhail، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2013
Pages
5
From page
3336
To page
3340
Abstract
We discovered a facile rearrangement of N-(hetero)aryl 2-imidazolines into diversely substituted imidazo[4,5-b]pyridines and benzimidazoles, under Bechamp reduction conditions. Combined with the earlier reported protocol for Pd-catalyzed (hetero)arylation of 2-imidazolines, it provides a simple two-step access to a range of compounds based on these medicinally important heterocyclic cores.
Keywords
Benzimidazoles , Pd-catalyzed arylation , N-(Hetero)aryl 2-imidazolines , Bechamp reduction , Rearrangement , 5-b]pyridines
Journal title
Tetrahedron Letters
Serial Year
2013
Journal title
Tetrahedron Letters
Record number
1884759
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