• Title of article

    A pair of unprecedented spiro-trisindole enantiomers fused through a five-member ring from Laurencia similis

  • Author/Authors

    Sun، نويسنده , , Wen-Shuang and Su، نويسنده , , Shan and Zhu، نويسنده , , Rong-Xiu and Tu، نويسنده , , Guangzhong and Cheng، نويسنده , , Wei and Liang، نويسنده , , Hong and Guo، نويسنده , , Xiao Yu and Zhao، نويسنده , , Yuying and Zhang، نويسنده , , Qing-Ying، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2013
  • Pages
    4
  • From page
    3617
  • To page
    3620
  • Abstract
    Similisines A (1a) and B (1b), a pair of unprecedented polybrominated spiro-trisindole enantiomers fused through a five-member ring, along with seven known biologically related indole alkaloids, were isolated from Laurencia similis. The structures and absolute configurations of the enantiomers were elucidated by comprehensive spectroscopic analysis, computer modeling, and comparison of experimental and theoretically calculated ECD. The proposed biogenetic pathway of 1a and 1b and cytotoxic activity of all isolates were also discussed.
  • Keywords
    Similisine B , Similisine A , Laurencia similis , Spiro-trisindole enantiomer
  • Journal title
    Tetrahedron Letters
  • Serial Year
    2013
  • Journal title
    Tetrahedron Letters
  • Record number

    1884874