Title of article
Regioselective 6-detrimethylsilylation of per-O-TMS-protected carbohydrates in the presence of ammonium acetate
Author/Authors
Cui، نويسنده , , Yanli and Cheng، نويسنده , , Zhaodong and Mao، نويسنده , , Jianwei and Yu، نويسنده , , Yongping، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2013
Pages
3
From page
3831
To page
3833
Abstract
A convenient methodology has been developed for the regioselective removal of primary trimethylsilyl group (TMS) of various per-O-TMS-protected carbohydrates by inexpensive ammonium acetate. After acetylation and trichloroacetimidation of 6-hydroxyl sugar 1b, other TMS groups of 1d and 1c were inert to ammonium acetate in the same conditions, and this approach was also successfully applied in TMS-protected sphingosine.
Keywords
carbohydrates , regioselectivity , Glycosides , Desilylation , protecting groups
Journal title
Tetrahedron Letters
Serial Year
2013
Journal title
Tetrahedron Letters
Record number
1884963
Link To Document