Title of article
New neolignans and a lignan from Miliusa fragrans, and their anti-herpetic and cytotoxic activities
Author/Authors
Sawasdee، نويسنده , , Kanokporn and Chaowasku، نويسنده , , Tanawat and Lipipun، نويسنده , , Vimolmas and Dufat، نويسنده , , Thi-Hanh and Michel، نويسنده , , Sylvie and Likhitwitayawuid، نويسنده , , Kittisak، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2013
Pages
5
From page
4259
To page
4263
Abstract
Seven new neolignans and a new lignan were isolated from the leaves and the stems of Miliusa fragrans, along with nine known polyphenolic compounds. Their structures were established through analysis of spectroscopic data, including 1H and 13C NMR, COSY, NOESY, HSQC, HMBC, and HRMS. The isolates were also evaluated for their inhibitory activity against herpes simplex virus types 1 and 2 (HSV-1 and HSV-2) and their cytotoxicity against KB, MCF7, and NCI-H187 cancer cells.
Keywords
cytotoxicity , Miliusa fragrans , Neolignans , Lignan , Herpes simplex virus
Journal title
Tetrahedron Letters
Serial Year
2013
Journal title
Tetrahedron Letters
Record number
1885147
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