Title of article
Organocatalytic asymmetric sulfa-Michael addition of thiols to trans-3,3,3-trifluoropropenyl phenyl sulfone
Author/Authors
Fang، نويسنده , , Xin and Dong، نويسنده , , Xiuqin and Liu، نويسنده , , Yuan-Yuan and Wang، نويسنده , , Chun-Jiang، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2013
Pages
3
From page
4509
To page
4511
Abstract
The first asymmetric sulfa-Michael addition of thiols to trans-3,3,3-trifluoropropenyl phenyl sulfone for the construction of a unique stereogenic center bearing a trifluoromethyl group and a sulfur atom has been achieved in high yields and moderate to good enantioselectivities with 1 mol % bifunctional amine–thiourea catalyst.
Keywords
Asymmetric catalysis , Amine–thiourea catalyst , Sulfa-Michael addition , Trans-3 , 3-Trifluoropropenyl phenyl sulfone , 3 , Trifluoromethyl group
Journal title
Tetrahedron Letters
Serial Year
2013
Journal title
Tetrahedron Letters
Record number
1885252
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