Title of article
Expanding the scope of silane-mediated hydrodehalogenation reactions
Author/Authors
Noonan، نويسنده , , Gary M. and Hayter، نويسنده , , Barry R. and Campbell، نويسنده , , Andrew D. and Gorman، نويسنده , , Timothy W. and Partridge، نويسنده , , Benjamin E. and Lamont، نويسنده , , Gill M. Anlezark، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2013
Pages
4
From page
4518
To page
4521
Abstract
A palladium-catalysed, silane-mediated hydrodehalogenation (HDH) reaction with increased substrate scope has been developed. Whereas previous attempts to reduce carboxylic acid or phenol-containing aryl halides using silane-based HDH conditions failed, the current protocol allows efficient access to the reduced products. Chemoselective HDH in the presence of sensitive functional groups is also presented.
Keywords
Hydrodehalogenation , Palladium catalysed , silane
Journal title
Tetrahedron Letters
Serial Year
2013
Journal title
Tetrahedron Letters
Record number
1885257
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