Title of article
T3P®-promoted Kabachnik–Fields reaction: an efficient synthesis of α-aminophosphonates
Author/Authors
Milen، نويسنده , , Mلtyلs and ءbrلnyi-Balogh، نويسنده , , Péter and Dancsَ، نويسنده , , Andrلs and Frigyes، نويسنده , , Dلvid and Pongَ، نويسنده , , Lلszlَ and Keglevich، نويسنده , , Gyِrgy، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2013
Pages
4
From page
5430
To page
5433
Abstract
A simple and efficient synthesis of α-aminophosphonates has been developed via the one-pot three-component reactions of aldehydes, amines, and trialkyl phosphites. The reactions occurred rapidly at room temperature in the presence of 1 equiv of propylphosphonic anhydride (T3P®) as the condensing agent, and the α-aminophosphonate products were obtained in high yields.
Keywords
Kabachnik–Fields reaction , Three-component condensation , T3P® , Mechanism , ?-Aminophosphonates
Journal title
Tetrahedron Letters
Serial Year
2013
Journal title
Tetrahedron Letters
Record number
1885614
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