Title of article
Osmium (VI) catalyzed chemoselective oxidation of allylic and benzylic alcohols
Author/Authors
Devari، نويسنده , , Shekaraiah and Deshidi، نويسنده , , Ramesh and Kumar، نويسنده , , Manjeet and Kumar، نويسنده , , Arvind K. Sharma، نويسنده , , Simmi and Rizvi، نويسنده , , Masood and Kushwaha، نويسنده , , Manoj Kumar Gupta، نويسنده , , Ajai Prakash and Shah، نويسنده , , Bhahwal Ali and Mahajan، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2013
Pages
4
From page
6407
To page
6410
Abstract
A mild and highly chemoselective approach to oxidation of allylic, electron rich/deficient benzylic, and heterocyclic alcohols employing catalytic quantities of K2[OsO2(OH)4] (3 mol %) and chloramine-T (50 mol %) is described. The protocol offers short reaction times (25 min–2 h), controlled oxidation, and tolerance to a variety of substrates. A systematic mechanistic study based on the LC-ESI-MS/MS reveals the presence of imidotriooxoosmium species which further reacts with alcohol to give the oxidized product.
Keywords
Allylic alcohols , Chemoselective , Oxidation , Chloramine-T
Journal title
Tetrahedron Letters
Serial Year
2013
Journal title
Tetrahedron Letters
Record number
1886655
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