Title of article
Copper-catalyzed tandem intramolecular cyclization/coupling reaction: solvent effect on reaction pathway
Author/Authors
Yamashita، نويسنده , , Mitsuaki and Noro، نويسنده , , Toshiaki and Iida، نويسنده , , Akira، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2013
Pages
4
From page
6848
To page
6851
Abstract
In this study, we developed direct methods for the synthesis of 3-substituted indoles from o-alkynylanilines by utilizing a copper-catalyzed tandem intramolecular cyclization/coupling reaction under mild and simple reaction conditions. Our investigation revealed that choice of the aprotic polar solvents and additives such as camphorsulfonic acid is critical in this reaction.
Keywords
Coupling reaction , indoles , cyclization , Copper
Journal title
Tetrahedron Letters
Serial Year
2013
Journal title
Tetrahedron Letters
Record number
1886916
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