Title of article
A one-pot two-step microwave-assisted synthesis of N1-substituted 5,6-ring-fused 2-pyridones
Author/Authors
Radi، نويسنده , , Marco and Vallerini، نويسنده , , Gian Paolo and Petrelli، نويسنده , , Alessia and Vincetti، نويسنده , , Paolo and Costantino، نويسنده , , Gabriele، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2013
Pages
4
From page
6905
To page
6908
Abstract
A fast, versatile and practical one-pot, two-step microwave-assisted protocol for the direct synthesis of N1-substituted 5,6-ring-fused 2-pyridones has been developed. The present method proved to be effective on a series of commercially available aldehydes, ketones and amines and could be profitably exploited in drug-discovery settings for the rapid identification of biologically relevant hit compounds.
Keywords
Ring-fused , One-pot two-step , N1-substituted , multicomponent reaction , microwave , 2-pyridones
Journal title
Tetrahedron Letters
Serial Year
2013
Journal title
Tetrahedron Letters
Record number
1886952
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