Title of article
Three-component diastereoselective cascade synthesis of thiohydantoins
Author/Authors
Ceban، نويسنده , , Victor and Hands، نويسنده , , Kane and Meazza، نويسنده , , Marta and Light، نويسنده , , Mark E. and Rios، نويسنده , , Ramon، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2013
Pages
5
From page
7183
To page
7187
Abstract
A new three-component cascade reaction for the synthesis of thiohydantoins is reported. The reaction between α-amino esters, nitrostyrenes, and aromatic isothiocyanates is efficiently promoted by organic bases to afford highly substituted thiohydantoins in moderate to good yields and diastereoselectivities.
Keywords
organocatalysis , cascade reactions , Thiohydantoins , Edman degradation , diastereoselective
Journal title
Tetrahedron Letters
Serial Year
2013
Journal title
Tetrahedron Letters
Record number
1887077
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