Title of article
Total synthesis of ribisin A
Author/Authors
Zhang، نويسنده , , Chaoli and Liu، نويسنده , , Jun and Du، نويسنده , , Yuguo، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2014
Pages
3
From page
959
To page
961
Abstract
The first total synthesis of natural product ribisin A has been achieved in 11 steps from commercially available methyl α-d-glucopyranoside with 21.6% overall yield. The highly oxygenated benzofuran skeleton of this natural product was constructed, taking advantages of the inherent chirality of d-glucose, through the key reactions of Ferrier carbocyclization, Johnson iodination, Suzuki cross-coupling, and Wacker oxidative cyclization.
Keywords
benzofuran , Ferrier carbocyclization , total synthesis , Wacker oxidation , Ribisin A
Journal title
Tetrahedron Letters
Serial Year
2014
Journal title
Tetrahedron Letters
Record number
1888020
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