Title of article
Synthesis of the 6-6-6 tricyclic skeleton of the anti-influenza A diterpene wickerol A
Author/Authors
Kwong Jia Ye، نويسنده , , Danson and Richard، نويسنده , , Jean-Alexandre، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2014
Pages
4
From page
2183
To page
2186
Abstract
A five-step synthesis of the 6-6-6 tricyclic skeleton of the diterpene wickerol A is described. The synthesis features a diastereoselective d-proline-mediated Robinson annulation and N-heterocyclic carbene-catalyzed Stetter reaction as key transformations to give the tricyclic carbon skeleton of this promising anti-influenza A natural product.
Keywords
natural products , Diterpene , Influenza A , Wickerol A , antivirals
Journal title
Tetrahedron Letters
Serial Year
2014
Journal title
Tetrahedron Letters
Record number
1888797
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