Title of article
Synthesis of substituted γ-lactam via Pd(0)-catalyzed cyclization of alkene-tethered carbamoyl chloride
Author/Authors
Chen، نويسنده , , Chen and Hu، نويسنده , , Jian and Su، نويسنده , , Jianhua and Tong، نويسنده , , Xiaofeng، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2014
Pages
3
From page
3229
To page
3231
Abstract
Pd(0)-catalyzed carboiodonation of but-3-enylcarbamic chloride has been developed with NaI as additive, which provides a ready access to substituted γ-lactam bearing an alkyl iodide group. This reaction features alkyl iodide reductive elimination as a key step in catalytic cycle, indicating the crucial role of additive NaI.
Keywords
Palladium catalysis , Carboiodonation , cyclization , ?-Lactam
Journal title
Tetrahedron Letters
Serial Year
2014
Journal title
Tetrahedron Letters
Record number
1889588
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