Title of article
Asymmetric iridium-catalyzed hydrogenation of 2-methylindole using phosphite ligands
Author/Authors
Lyubimov، نويسنده , , Sergey E. and Ozolin، نويسنده , , Dmitry V. and Davankov، نويسنده , , Vadim A.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2014
Pages
2
From page
3613
To page
3614
Abstract
The iridium-catalyzed asymmetric hydrogenation of 2-methylindole using monodentate phosphites and amidophosphites as ligands was examined. The use of iodine as the additive resulted in increased enantioselectivity and conversion in the iridium-catalyzed hydrogenation of 2-methylindole. Full conversion and up to 80% ee were obtained with a catalyst based on a phosphite ligand.
Keywords
iridium , Phosphites , asymmetric hydrogenation , 2-Methylindole
Journal title
Tetrahedron Letters
Serial Year
2014
Journal title
Tetrahedron Letters
Record number
1889827
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