Title of article
Formal synthesis of osladin based on an activation relay process
Author/Authors
Zhang، نويسنده , , Xiaofei and Wu، نويسنده , , Jing-Jing and Shi، نويسنده , , Yong and Lin، نويسنده , , Jing-Rong and Tian، نويسنده , , Wei-Sheng، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2014
Pages
4
From page
4639
To page
4642
Abstract
An efficient five-step formal synthesis of osladin by utilizing the intact skeleton of diosgenin acetate is reported. Key features of this study include an unprecedented reductive opening of E-ring in steroidal sapogenin to give 22S-5, and an activation relay process for selective breakage of C16O bond in furostanol to deliver 22R-17.
Keywords
Intact skeleton , Activation relay process , Osladin , E-ring opening , Steroid
Journal title
Tetrahedron Letters
Serial Year
2014
Journal title
Tetrahedron Letters
Record number
1890391
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