Title of article
A one-pot tandem synthesis of various 1,2-disubstituted benzimidazoles
Author/Authors
Yeong، نويسنده , , Keng Yoon and Ali، نويسنده , , Mohamed Ashraf and Ang، نويسنده , , Chee Wei and Tan، نويسنده , , Soo Choon and Osman، نويسنده , , Hasnah، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2014
Pages
4
From page
4697
To page
4700
Abstract
A facile method to synthesize various 1,2-disubstituted benzimidazoles is developed. It is suggested that formation of a Meisenheimer adduct between the substrate, amine, and solvent aids the N-arylation process. The generality of the protocol is demonstrated by the efficient reactions involving numerous substituents ranging from electron-withdrawing groups to electron-donating groups.
Keywords
cycloaddition , Tandem synthesis , Substituted benzimidazoles
Journal title
Tetrahedron Letters
Serial Year
2014
Journal title
Tetrahedron Letters
Record number
1890413
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