Title of article
Copper-catalyzed decarboxylative coupling reactions for the synthesis of propargyl amines
Author/Authors
Lim، نويسنده , , Jeongah and Park، نويسنده , , Kyungho and Byeun، نويسنده , , Aleum and Lee، نويسنده , , Sunwoo، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2014
Pages
4
From page
4875
To page
4878
Abstract
When aryl alkynyl carboxylic acids were allowed to react with amines and aldehydes in CH3CN at 80 °C in the presence of 10 mol % CuI, the desired propargyl amines were formed in good yields. This coupling reaction demonstrated to work across a broad range of reagents including functionalized aryl alkynyl carboxylic acids, aliphatic and aromatic aldehydes, and cyclic and acyclic amines.
Keywords
Decarboxylative coupling , Alkynyl carboxylic acid , Propargyl amine , Copper , A3 coupling
Journal title
Tetrahedron Letters
Serial Year
2014
Journal title
Tetrahedron Letters
Record number
1890489
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