Title of article
A novel Prins reaction for the synthesis of hexahydro-8,8-dimethyl-1H-isochromen-7-ol derivatives
Author/Authors
Reddy، نويسنده , , B.V. Subba and Rehana Anjum، نويسنده , , S. and Madhusudhan Reddy، نويسنده , , G. and Sridhar، نويسنده , , B.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2014
Pages
3
From page
5011
To page
5013
Abstract
Various aldehydes undergo smooth coupling with 5-(hydroxymethyl)-4,6,6-trimethylcyclohex-3-enol in the presence of p-TSA at ambient temperature to afford a novel series of hexahydro-8,8-dimethyl-1H-isochromen-7-ol derivatives in good yields with high selectivity. This is the first report on the synthesis of isochromen-7-ol derivatives via the Prins reaction.
Keywords
Bicycles , Hexahydro-1H-isochromen-7-ols , Bronsted acid catalysis , Prins cyclization
Journal title
Tetrahedron Letters
Serial Year
2014
Journal title
Tetrahedron Letters
Record number
1890557
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