Title of article
A new, one-pot, multicomponent synthesis of 5-aza-9-deaza-adenines under microwave irradiation
Author/Authors
Lim، نويسنده , , Felicia Phei Lin and Luna، نويسنده , , Giuseppe and Dolzhenko، نويسنده , , Anton V.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2014
Pages
5
From page
5159
To page
5163
Abstract
A new, practical, three-component method for the synthesis of 5-aza-9-deaza-adenines is developed. Aminopyrazoles react in a one-pot fashion with triethyl orthoformate and cyanamide under microwave irradiation affording 5-aza-9-deaza-adenines in good yields and high purity. The main advantages of this method are the operational simplicity, accessibility, and high efficiency.
Keywords
Cyanamide , Pyrazole , Purine analogue , Triazine , multicomponent reaction
Journal title
Tetrahedron Letters
Serial Year
2014
Journal title
Tetrahedron Letters
Record number
1890623
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