Title of article
Rh(II) acetate catalyzed cyclopropanation of styrenes with enaldiazo esters: diastereoselective synthesis of enal-cyclopropanes
Author/Authors
Rathore، نويسنده , , Kuldeep Singh and Katukojvala، نويسنده , , Sreenivas، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2014
Pages
3
From page
6370
To page
6372
Abstract
An efficient Rh(II) acetate catalyzed highly diastereoselective cyclopropanation of styrenes with enaldiazo esters has been developed (up to >95:5 dr and 62–82% yield). The reaction is proposed to involve diacceptor electrophilic rhodium enalcarbenoids and constitutes the first direct synthesis of enal-cyclopropanes with an all carbon γ-quaternary stereocenter.
Keywords
enals , Carbenes , Cyclopropanes , diazo compounds , Enalcarbenoids
Journal title
Tetrahedron Letters
Serial Year
2014
Journal title
Tetrahedron Letters
Record number
1891202
Link To Document