Title of article
Seven- and eight-membered heterocyclic biaryl synthesis through a metal-free oxidative coupling reaction
Author/Authors
Sun، نويسنده , , Shutao and Yang، نويسنده , , Jingjing and Li، نويسنده , , Fanmei and Lv، نويسنده , , Zheng and Li، نويسنده , , Wei and Lou، نويسنده , , Hongxiang and Liu، نويسنده , , Lei، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2014
Pages
4
From page
6899
To page
6902
Abstract
A metal-free intramolecular biaryl coupling mediated by DDQ and BF3·OEt2 was developed. The reaction proceeds smoothly at room temperature to give seven- and eight-membered heterocyclic biaryl compounds in up to 95% yields. Only 1 equiv of DDQ sufficed for the reaction, obviating the use of a large excess of oxidants and undesired chlorination pathway in metal-mediated process.
Keywords
Intramolecular , Biaryl coupling , Metal-free , Heterocyclic , Seven- and eight-membered ring
Journal title
Tetrahedron Letters
Serial Year
2014
Journal title
Tetrahedron Letters
Record number
1891424
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