Title of article
A concise synthesis of Ni-didecarboxysirohydrochlorin hexamethylester—a model compound for key intermediates in heme d1 and heme biosynthesis
Author/Authors
Vu، نويسنده , , Nghiem Hai and Lork، نويسنده , , Enno and Montforts، نويسنده , , Franz-Peter، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2014
Pages
4
From page
6911
To page
6914
Abstract
An efficient synthesis of Ni-didecarboxysirohydrochlorin hexamethylester rac-13 was achieved by Barton olefination starting from a readily available dioxo-isobacteriochlorin rac-9. The synthetic route should open a general facile access to this type of naturally occurring hydroporphyrins. Isobacteriochlorins 3–6 are key intermediates in heme d1 and heme biosynthesis of sulfate reducing and denitrifying bacteria as well as in archaebacteria.
Keywords
Sirohydrochlorin , Heme d1 , Heme , Didecarboxysirohydrochlorin , Barton olefination
Journal title
Tetrahedron Letters
Serial Year
2014
Journal title
Tetrahedron Letters
Record number
1891429
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