Title of article
Diastereoselective synthesis of β-aminosulfones from the 1,2-addition to N-(para-methoxyphenyl) imines
Author/Authors
Anderson، نويسنده , , James C. and Campbell، نويسنده , , Ian B. and Campos، نويسنده , , Sebastien and Shannon، نويسنده , , Jonathan، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2014
Pages
3
From page
7206
To page
7208
Abstract
The base-promoted 1,2-addition of alkyl phenylsulfones to N-(para-methoxyphenyl) imines was investigated as a direct route to stereochemically defined β-aminosulfones. Using nBuLi as base, 2-(phenylsulfonyl)ethylbenzene was added to a range of N-(para-methoxyphenyl) imines to give β-aminosulfone products in high yields as single anti-diastereoisomers. Other less substituted alkyl phenylsulfones were not as successful.
Keywords
1 , 2-addition , ?-Aminosulfone , Imine , Sulfone , diastereoselective
Journal title
Tetrahedron Letters
Serial Year
2014
Journal title
Tetrahedron Letters
Record number
1893590
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