• Title of article

    Asymmetric synthesis of 2-substituted cyclic amines

  • Author/Authors

    Kudale، نويسنده , , Amit A. and Anaspure، نويسنده , , Prasad and Goswami، نويسنده , , Falguni and Voss، نويسنده , , Matthew، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2014
  • Pages
    3
  • From page
    7219
  • To page
    7221
  • Abstract
    Cyanomethylenetributylphosphorane-mediated ring closure for the asymmetric synthesis of 2-substituted cyclic amines such as azetidines, pyrrolidines and a piperidine is reported. The desired stereochemistry at the 2-position was fixed using (S)-tert-butyl sulfinamide as a chiral auxiliary.
  • Keywords
    chiral auxiliary , asymmetric synthesis , Cyclic amines , Cyanomethylenetributylphosphorane
  • Journal title
    Tetrahedron Letters
  • Serial Year
    2014
  • Journal title
    Tetrahedron Letters
  • Record number

    1893593