Title of article
Asymmetric synthesis of 2-substituted cyclic amines
Author/Authors
Kudale، نويسنده , , Amit A. and Anaspure، نويسنده , , Prasad and Goswami، نويسنده , , Falguni and Voss، نويسنده , , Matthew، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2014
Pages
3
From page
7219
To page
7221
Abstract
Cyanomethylenetributylphosphorane-mediated ring closure for the asymmetric synthesis of 2-substituted cyclic amines such as azetidines, pyrrolidines and a piperidine is reported. The desired stereochemistry at the 2-position was fixed using (S)-tert-butyl sulfinamide as a chiral auxiliary.
Keywords
chiral auxiliary , asymmetric synthesis , Cyclic amines , Cyanomethylenetributylphosphorane
Journal title
Tetrahedron Letters
Serial Year
2014
Journal title
Tetrahedron Letters
Record number
1893593
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