Epidemiologic concerns relative to in vivo and in vitro production of livestock embryos

Evidence indicates low potential for transmission of pathogens with in vivo-derived embryos of cattle when appropriate precautions are taken. In apparent contrast, results of research with in vivo-derived embryos of small ruminants and swine and with in vitro-derived embryos of cattle suggest a greater tendency for their association with pathogens after artificial exposure. However, regardless of donor species, investigations involving collection of embryos from artificially or naturally infected animals and assessment of health of recipients and offspring after transfer of these embryos have indicated low potential for transmitting disease. s paper, results of embryo–pathogen research are summarized, emphasizing potential for spread of pathogens under natural circumstances. Also, safe embryo handling practices and their application to multiple species are discussed.