An isodesmic reaction based approach to aromaticity of a large spectrum of molecules

A new thermodynamic scale of aromaticity is devised for a large spectrum of organic molecules using isodesmic reactions. The present scale named Earoma quantifies aromaticity as the average stabilization of a conjugated bond in a cyclic/extended cyclic conjugated system as compared to a matching linear conjugated one. The Earoma values showed good agreement with the HOMA, NICS0, NICS1, MESP, and ASE indices of aromaticity. Earoma scale offers an easy way to compare the aromaticity of molecules in different categories to that of benzene.