Title of article
Anti-androgenic activities of the triterpenoids fraction of Ganoderma lucidum
Author/Authors
Liu، نويسنده , , Jie and Shimizu، نويسنده , , Kuniyoshi and Konishi، نويسنده , , Fumiko and Noda، نويسنده , , Kiyoshi and Kumamoto، نويسنده , , Shoichiro and Kurashiki، نويسنده , , Kenji and Kondo، نويسنده , , Ryuichiro، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2007
Pages
6
From page
1691
To page
1696
Abstract
The ethanol extract of Ganoderma lucidum showed inhibitory activity on both isozymes (types 1 and 2) of 5α-reductase and suppression effects of ventral prostate growth induced by testosterone in castrated rat, but not induced by dihydrotestosterone. Activity-guided fractionation and TLC analysis suggested that the active principles in vivo were triterpenoids. These results indicate that the triterpenoids fraction of G. lucidum might be a useful ingredient in the treatment of benign prostatic hyperplasia.
Keywords
Anti-androgen activities , Triterpenoid , Ganoderma lucidum , 5?-Reductase , Benign Prostatic Hyperplasia
Journal title
Food Chemistry
Serial Year
2007
Journal title
Food Chemistry
Record number
1953672
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