Title of article
N-Methylation of adamantane-substituted oxalamide unit affects its conformational rigidity: A skew conformation of the oxalamide bridge
Author/Authors
D?oli?، نويسنده , , Zoran and Margeta، نويسنده , , Renato and Vinkovi?، نويسنده , , Marijana and ?tefani?، نويسنده , , Zoran and Koji?-Prodi?، نويسنده , , Biserka and Mlinari?-Majerski، نويسنده , , Kata and ?ini?، نويسنده , , Mladen، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2008
Pages
7
From page
218
To page
224
Abstract
The synthesis of adamantane functionalized retropeptides, N,N′-bis(2-adamantyl-2-carboxylic acid methyl ester)oxalamide (1) and N-methyl-N,N’-bis(2-adamantyl-2-carboxylic acid methyl ester)oxalamide (2), as well as the influence of the N-methylation on the conformational preferences of oxalamide group are described. In the solid state the oxalamide group of 1 is planar while in the retropeptide 2 adopts a skew-conformation.
Keywords
Retropeptides , N-Methylation , Adamantane , X-ray structure analysis , Oxalamides
Journal title
Journal of Molecular Structure
Serial Year
2008
Journal title
Journal of Molecular Structure
Record number
1964920
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