Title of article
Carbon nanotube-hydroxyapatite nanocomposite for DNA complexation
Author/Authors
Bhattarai، نويسنده , , Shanta Raj and Aryal، نويسنده , , Santosh and Bahadur K.C.، نويسنده , , Remant and Bhattarai، نويسنده , , Narayan and Han Hwang، نويسنده , , Pyong and Keun Yi، نويسنده , , Ho and Yong Kim، نويسنده , , Hak، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2008
Pages
6
From page
64
To page
69
Abstract
This communication reports that a plasmid DNA molecule could spontaneously interact with hydroxyapatite (HA) functionalized multi-walled carbon nanotubes (MWNTs-HA) in water-solute environment. Gel electrophoresis, UV absorption, FT-IR, and Raman spectra were used to characterize MWNTs-HA/DNA complexes. AFM and TEM images revealed that DNA induces the de-aggregation of MWNTs-HA. Our preliminary study suggests that the plasmid DNA significantly interacted with MWNTs-HA, and formed the stable complex, and could find the application in nanotechnology for gene delivery system.
Keywords
Biomaterials , Calcium compounds , Carbon nanotubes , Nanomaterials , DNA
Journal title
Materials Science and Engineering C
Serial Year
2008
Journal title
Materials Science and Engineering C
Record number
2096688
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