Title of article
Effect of implantation of biodegradable magnesium alloy on BMP-2 expression in bone of ovariectomized osteoporosis rats
Author/Authors
Guo، نويسنده , , Yue and Ren، نويسنده , , Ling and Liu، نويسنده , , Chang and Yuan، نويسنده , , Yajiang and Lin، نويسنده , , Xiao and Tan، نويسنده , , Lili and Chen، نويسنده , , Shurui and Yang، نويسنده , , Ke and Mei، نويسنده , , Xifan، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2013
Pages
5
From page
4470
To page
4474
Abstract
The study was focused on the implantation of a biodegradable AZ31 magnesium alloy into the femoral periosteal of the osteoporosis modeled rats. The experimental results showed that after 4 weeks implantation of AZ31 alloy in the osteoporosis modeled rats, the expression of BMP-2 in bone tissues of the rats was much enhanced, even higher than the control group, which should promote the bone formation and be beneficial for reducing the harmful effect of osteoporosis. Results of HE stains showed that the implantation of AZ31 alloy did not have obvious pathological changes on both the liver and kidney of the animal.
Keywords
Magnesium alloy , Osteoblast , BMP-2 , Osteoporosis
Journal title
Materials Science and Engineering C
Serial Year
2013
Journal title
Materials Science and Engineering C
Record number
2103612
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