Title of article
Luciferase expression 2 years after DNA injection in glass catfish (Kryptopterus bicirrhus)
Author/Authors
Dijkstra، نويسنده , , J.M. and Okamoto، نويسنده , , H. and Ototake، نويسنده , , M. and Nakanishi، نويسنده , , T.، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2001
Pages
4
From page
199
To page
202
Abstract
Glass catfish (Kryptopterus bicirrhus) have transparent muscles and skin. Intramuscular injection of DNA encoding luciferase into these fish induced luciferase expression that was measurable in vivo with a low light video image analyser. Expression could be detected up to at least 2 years after DNA injection. Although luciferase is not representative of all types of antigen, this study stresses the need for future studies directed to limit the period of antigen expression after DNA vaccination.
Keywords
DNA immunisation , luciferase , long term expression , glass catfish , in vivo assay
Journal title
Fish and Shellfish Immunology
Serial Year
2001
Journal title
Fish and Shellfish Immunology
Record number
2106627
Link To Document