Title of article
Lethality induced by stannous chloride on Escherichia coli AB 1157: Participation of reactive oxygen species
Author/Authors
Dantas، نويسنده , , F.J.S. and Moraes، نويسنده , , M.O. and Carvalho، نويسنده , , E.F. and Valsa، نويسنده , , J.O. and Bernardo-Filho، نويسنده , , M. and Caldeira-De-Araْjo، نويسنده , , A.، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1996
Pages
4
From page
959
To page
962
Abstract
Stannous chloride (SnCl2) has been widely used in nuclear medicine as a reducing agent of pharmaceutical products radiolabelled with technetium-99m. To verify whether the lethality induced by this salt could be mediated by reactive oxygen species (ROS), Escherichia coli cultures were treated with SnCl2 in the presence of catalase, ROS scavengers or metal-ion chelators. The inactivation effect, as measured by survival determination, was abolished by thiourea, sodium benzoate, dipyridyl or catalase. The results suggest the participation of ROS, generated by a Fenton-like reaction, in the lethal effect induced by SnCl2
Journal title
Food and Chemical Toxicology
Serial Year
1996
Journal title
Food and Chemical Toxicology
Record number
2115516
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