• Title of article

    Benefit–risk assessment of plant sterols in margarine: A QALIBRA case study

  • Author/Authors

    Hoekstra، نويسنده , , Jeljer and Fransen، نويسنده , , Heidi P. and van Eijkeren، نويسنده , , Jan C.H. and Verkaik-Kloosterman، نويسنده , , Janneke and de Jong، نويسنده , , Nynke and Owen، نويسنده , , Helen J. Kennedy، نويسنده , , Marc and Verhagen، نويسنده , , Hans and Hart، نويسنده , , Andy، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 2013
  • Pages
    8
  • From page
    35
  • To page
    42
  • Abstract
    This paper presents the benefit–risk assessment of adding plant sterols to margarine as an illustration of the QALIBRA method and software. With the QALIBRA tool health effects, risks as well as benefits are expressed in a common metric (DALY) which allows quantitative balancing of benefits and risks of food intake. The QALIBRA software can handle uncertainties in a probabilistic simulation. This simple case study illustrates the data need and assumptions that go into a quantitative benefit–risk assessment. The assessment shows that the benefits of plant sterols added to margarine outweigh the risks, if any.
  • Keywords
    Phytosterols , Benefit–risk assessment
  • Journal title
    Food and Chemical Toxicology
  • Serial Year
    2013
  • Journal title
    Food and Chemical Toxicology
  • Record number

    2124648