Title of article
Immunohistochemical reactivity of anti-platelet monoclonal antibodies
Author/Authors
Simon، نويسنده , , M. and Dusinsky، نويسنده , , R. and Horovska، نويسنده , , L. and Bilka، نويسنده , , F. and Hluchy، نويسنده , , S.، نويسنده ,
Issue Information
سالنامه با شماره پیاپی سال 1996
Pages
6
From page
377
To page
382
Abstract
Ten mAbs of preliminary clusters PC13 and PC27 with specificity for bovine platelets were studied by immunohistochemistry. Cryostat sections of bovine lymph node, spleen, thymus, small intestine, liver, kidney and smears of bone marrow cells were used. Five mAbs (CAPP2, IVA30, IVA125, IL-A164 and IL-A166) assigned to cluster PC13 (CD41/CD61) stained platelets and non-lymphocytic cells of various tissues. Our data confirm the presence of two specificities in PC27: three mAbs (IVA120, IVA197 and IVA198) specific for fibrinogen strongly reacted with the endothelial and reticular tissues whereas the other two mAbs Co-3D1D4 and Buf13 (WC13) were negative.
Keywords
cattle , CD , fibrinogen , Histochemistry , Monoclonal antibodies
Journal title
Veterinary Immunology and Immunopathology
Serial Year
1996
Journal title
Veterinary Immunology and Immunopathology
Record number
2160079
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