Title of article
Identifying markers of pathology in SAXS data of malignant tissues of the brain
Author/Authors
Siu، نويسنده , , K.K.W. and Butler، نويسنده , , S.M. and Beveridge، نويسنده , , T. and Gillam، نويسنده , , J.E. and Hall، نويسنده , , C.J. and Kaye، نويسنده , , A.H. and Lewis، نويسنده , , R.A. and Mannan، نويسنده , , K. and McLoughlin، نويسنده , , G. and Pearson، نويسنده , , S. D. Round، نويسنده , , A.R. and Schültke، نويسنده , , E. and Webb، نويسنده , , G.I. and Wilkinson، نويسنده , , S.J.، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2005
Pages
7
From page
140
To page
146
Abstract
Conventional neuropathological analysis for brain malignancies is heavily reliant on the observation of morphological abnormalities, observed in thin, stained sections of tissue. Small Angle X-ray Scattering (SAXS) data provide an alternative means of distinguishing pathology by examining the ultra-structural (nanometer length scales) characteristics of tissue. To evaluate the diagnostic potential of SAXS for brain tumors, data was collected from normal, malignant and benign tissues of the human brain at station 2.1 of the Daresbury Laboratory Synchrotron Radiation Source and subjected to data mining and multivariate statistical analysis. The results suggest SAXS data may be an effective classifier of malignancy.
Keywords
Brain tumors , DATA MINING , Synchrotron radiation , small angle X-ray scattering
Journal title
Nuclear Instruments and Methods in Physics Research Section A
Serial Year
2005
Journal title
Nuclear Instruments and Methods in Physics Research Section A
Record number
2203871
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