Simultaneous Determination of Ascorbic Acid, Paracetamol and Phenylephrine: Carbon Nanotubes Ceramic Electrode as a Renewable Electrode

In this paper, we fabricated a renewable and mechanical rigid electrode that we named it carbon nanotubes ceramic electrode (CNTsCE). The physicochemical properties of the obtained electrode were characterized by scanning electron microscopy and electrochemical methods. Comparing with carbon powder ceramic electrode (CPCE), the CNTsCE exhibited excellent electrochemical catalytic activities for the oxidation of ascorbic acid (AA), paracetamol (PA) and phenylephrine (PP) and three well shaped and separated anodic peaks were observed. Differential pulse voltammetry (DPV) technique was employed for the simultaneous determination of AA, PA and PP and the obtained results confirmed that the oxidation peak currents increased linearly with AA, PA and PP concentrations in the ranges of 5.0-350.0, 0.1-3.5 and 1.0-70.0 ?M with detection limit of 2.0, 0.04 and 0.3 ?M for AA, PA and PP, respectively. Finally, the CNTsCE was successfully used for the determination of AA, PA and PP in biological and pharmaceutical samples