• Title of article

    Preparation of E-1,3-diaminoethenyl functional groups by the reaction of enol tosylate of alpha-formylglycine with primary and secondary amines

  • Author/Authors

    Bhavaraju، Sitaram نويسنده 51 Lower College Road, Dept. of Chemistry, University of Rhode Island, Kingston, RI-02881, USA ,

  • Issue Information
    فصلنامه با شماره پیاپی 18 سال 2016
  • Pages
    12
  • From page
    59
  • To page
    70
  • Abstract
    The E-1,3-diaminoethenyl functional group is a potentially useful synthon. A number of examples of E-1,3-diaminoethenyl functional groups were prepared in good yield starting from an E-enol tosylate of a serine based diketopiperazine and 1°- or 2° amine nucleophiles. The reaction proceeds via a stereoselective nucleophilic substitution pathway.
  • Journal title
    Current Chemistry Letters
  • Serial Year
    2016
  • Journal title
    Current Chemistry Letters
  • Record number

    2380922