• Title of article

    Analysis of IL-33 gene polymorphism (rs11792633 C/T) and risk of schizophrenia

  • Author/Authors

    -، - نويسنده University of sistan and Baluchestan Kordi-Tamandani, DorMohammad , -، - نويسنده university of Ferdowssi,Mashhad, Iran Bahrami, Ahmad Reza , -، - نويسنده university of Ferdowssi,Mashhad, Iran Sabbaghi-ghale-no, Raziye , -، - نويسنده University of sistan and Baluchestan Soleimani, Hanieh , -، - نويسنده University of sistan and Baluchestan Baranzehi, Tayebe

  • Issue Information
    فصلنامه با شماره پیاپی 0 سال 2016
  • Pages
    4
  • From page
    45
  • To page
    48
  • Abstract
    -
  • Abstract
    Recently, inflammation has been found to be a significant factor in the development of Schizophrenia (SCZ). The aim of the present research was to investigate whether interleukin-33 (IL-33, OMIM: 608678) gene polymorphism (rs11792633, C/T) is associated with the development of SCZ or not.DNA was isolated from the serum of 70 patients with SCZ and 70 healthy controls. The PCR based method was used for detection of the IL-33 polymorphism. The CT (OR=0.05, 95% CI: 0.003-0.057, P<0.001) andTT(OR=0.12, 95% CI: 0.028-0.46, P<0.001) genotypes significantly decreased the risk of SCZ. Our present findings indicate that the IL-33 polymorphism associated with the risk of SCZ.
  • Journal title
    Molecular Biology Research Communications
  • Serial Year
    2016
  • Journal title
    Molecular Biology Research Communications
  • Record number

    2386607

    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=2386607