Title of article
The Role of Interleukin-17A (IL-17A) in Depression
Author/Authors
Fathalizadeh، Javad نويسنده Immunology of Infectious Diseases Research Center, Rafsanjan University of Medical Sciences, Rafsanjan, IR Iran , , Fathalizadeh، Hanieh نويسنده School of Psychology, Azarbaijan Shahid Madani University, Tabriz, IR Iran , , Mirzabeigi، Mohammadreza نويسنده Immunology of Infectious Diseases Research Center, Rafsanjan University of Medical Sciences, Rafsanjan, IR Iran , , Hakimi ، Hamid نويسنده Dept. of Microbiology, School of Medicine, Rafsanjan University of Medical Sciences, Rafsanjan, Iran. , , Kazemi Arababadi، Mohammad نويسنده ,
Issue Information
ماهنامه با شماره پیاپی 0 سال 2016
Pages
4
From page
1
To page
4
Abstract
The aim of this review was to address the recent data regarding the
role of IL-17A in the pathogenesis of depression and its complications,
such as cancer. This review article summarizes the recent data on the
role of IL-17A in depression, using the PubMed and Google Scholar
databases. It has been documented that depression may alter the immune
response via unknown mechanism/s. It is possible that immune responses
and depression are linked via several molecules, including cytokines.
IL-17A, a pro-inflammatory cytokine, participates in the pathogenesis of
several inflammatory-based diseases, such as autoimmunity. Due to the
comorbidity of depression and chronic inflammatory processes, and
depression’s effect on the immune system, it may be hypothesized that
the IL-17A cytokine plays a key role in the pathogenesis of
depression.
Journal title
Iranian Red Crescent Medical Journal
Serial Year
2016
Journal title
Iranian Red Crescent Medical Journal
Record number
2399671
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