Title of article
Fast one-pot synthesis of 1,8-dioxo-decahydroacridine derivatives using sulfonic acid functionalized LUS-1 and the study on their antimicrobial activities
Author/Authors
Mohammadi Ziarani، Ghodsi نويسنده Department of Chemistry, Alzahra University, Tehran, Iran , , Rahimifard، Mahshid نويسنده Department of Chemistry,Alzahra University,Tehran,Iran , , Badiei، Alireza نويسنده School of Chemistry, College of Science,University of Tehran,Tehran,Iran , , Abolhasani Soorki، Ali نويسنده Academic Center for Education, Culture and Research (ACECR), Research Institute of Applied Sciences,Shahid Beheshti University,Tehran,Iran ,
Issue Information
فصلنامه با شماره پیاپی سال 2016
Pages
7
From page
369
To page
375
Abstract
Mesoporous silica LUS-1 (Laval University Silica) was successfully functionalized by propyl sulfonic acid and was used as a recyclable catalyst for the synthesis of acridine-1,8-diones via a pseudo four component reaction of aromatic aldehydes, dimedone and ammonium acetate (or anilines). The excellent yields, short reaction time, simple work-up procedure, and environmentally friendly conditions are advantages of this method. All synthesized compounds were screened for antimicrobial and antifungal activities. Only compound 3e exhibited activity against Bacillus subtilis.
Keywords
8-dione , Dimedone , Nanoporous acid catalyst , sulfonic acid functionalized LUS-1 , Acridine-1
Journal title
Iranian Journal of Catalysis
Serial Year
2016
Journal title
Iranian Journal of Catalysis
Record number
2400399
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