Title of article
Effects of Coenzyme Q10 on Hemoglobin A1C, Serum Urea and Creatinine in Alloxan-Induced Type 1 Diabetic Rats
Author/Authors
AHMADVAND, HASSAN Department of Biochemistry - Faculty of Medicine - Lorestan University of Medical Sciences, Khoram Abad, Iran
Pages
4
From page
64
To page
67
Abstract
Coenzyme Q10 is a natural antioxidant and free radicals scavenger. In the present study, we examined
effect of coenzyme Q10 on hemoglobin A1C, serum urea and creatinine in alloxan-induced Type 1 diabetic
rats. Thirty Sprage-Dawley male rats were divided into three groups randomly; group one as control,
group two diabetic untreatment, and group three treatments with coenzyme Q10 (15 mg/kg i.p daily),
respectively. Diabetes was induced in the second and third groups by alloxan injection subcutaneously.
After 8 weeks, animals were anaesthetized; blood samples were collected to measure the
hemoglobin A1C, serum glucose, urea and creatinine. Coenzyme Q10 significantly decreased hemoglobin
A1C, serum glucose, urea and creatinine. Coenzyme Q10 exerts beneficial effects on the hemoglobin A1C
and serum glucose in alloxan-induced type 1 diabetic rats.
Keywords
Diabetes , Hemoglobin A1C , Serum , Glucose , Coenzyme Q10 , Rat
Journal title
Astroparticle Physics
Serial Year
2012
Record number
2414065
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