Title of article
Genotoxicity, Bioactivity and Clinical Properties of Calcium Silicate Based Sealers: A Literature Review
Author/Authors
Jafari, Farnaz Department of Endodontics - Dental School, Tabriz Branch - Islamic Azad University, Tabriz , Jafari, Sanaz Department of Orthodontics - Dental School, Ilam University of Medical Sciences , Etesamnia, Paria Department of Operative Dentistry - Dental School, Tabriz Branch - Islamic Azad University, Tabriz
Pages
7
From page
407
To page
413
Abstract
An ideal endodontic sealer should have many properties such as excellent seal after setting,
dimensional stability, slow setting time to ensure sufficient working time, insolubility to tissue
fluids, adequate adhesion with canal walls and biocompatibility. Genotoxicity is one of the
important factors that influence biocompatibility of an endodontic sealer. This literature
review was conducted to survey the genotoxicity, bioactivity and clinical perspectives of
calcium silicate based sealers. We searched PubMed using appropriate MeSH keywords. Also
a hand search was conducted in the related journals. Sixty eight articles were assessed finally.
Genotoxicity and acute inflammation were high in calcium silicate based sealers. Both resinbased
and calcium silicate based sealers caused perceptible tooth discoloration. There were
controversies regarding the fracture resistance, apical patency and retreatability of different
sealers. Clinical properties of calcium silicate-based sealers are also outlined.
Keywords
Bioactive Materials , Genotoxicity , Mineral Trioxide Aggregate , Root Canal Sealers , Tricalcium Silicate
Journal title
Astroparticle Physics
Serial Year
2017
Record number
2425413
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