Comparison of Desensitizing Efficacy of an Iranian Dentifrice and a Commercially Available Dentifrice: A Randomized Double-Blinded Controlled Clinical Trial

Objective: The aim of this randomized controlled clinical trial was to investigate the effect of a new Iranian toothpaste and a commercially available toothpaste containing desensitizing agent (5% potassium nitrate) on dentine hypersensitivity in a 24-week study. Materials and Methods: Fifty healthy volunteers, who had at least two sensitive root surfaces, completed the study period. The participants were randomly given one of the two toothpastes; Iranian (antihypersensitive Pooneh) or commercially available (fresh mint Sensodyne) toothpaste. Visual analogue scales (VASs) indi- cating the intensity of tooth hypersensitivity responding to tactile, airblast and cold-water stimuli were examined at baseline and weeks 2, 4, 12 and 24. Results: Overall, VAS scores for tactile, airblast, and cold-water tests significant- ly reduced compared with the baseline in both groups (all P values <0.001). However, there was no significant difference between the two groups regarding the measured parameters. Conclusion: This study demonstrated that the Iranian dentifrice (antihypersensi- tive Pooneh) was as effective as the commercially available one (fresh mint Sen- sodyne) in reducing tooth hypersensitivity.