Title of article
Bronsted Acidic Ionic Liquid: An Efficient and Reusable Catalyst for the Multi-Component Solvent-Free Synthesis of Dihydropyrimidinones
Author/Authors
Alinezhad, Heshmatollah Department of Organic Chemistry - Faculty of Chemistry - University of Mazandaran, Babolsar, Iran , Ghobadi, Neda Department of Organic Chemistry - Faculty of Chemistry - University of Mazandaran, Babolsar, Iran
Pages
8
From page
12
To page
19
Abstract
An efficient and convenient procedure for the synthesis of 3,4-dihydropyrimidin-2(1H)-ones and thiones by condensation of 1,3-dicarbonyl compounds, Aromatic and aliphatic aldehydes, and urea or thiourea in the presence of catalytic amount of Brønsted acidic ionic liquid 3-methyl-1-sulfonic acid imidazolium chloride {[Msim]Cl} under thermal solvent-free conditions reacted easily to afford the corresponding 3,4-dihydropyrimidin-2(1H)-ones and thiones. Straightforward and clean workup, short reaction time, good to excellent yields and reusability of the catalyst are the advantages of this method.
Keywords
thiourea , reusable catalyst , Brønsted acidic , Ionic liquid , Dihydropyrimidinone
Journal title
Astroparticle Physics
Serial Year
2016
Record number
2428311
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