Orbitofrontal Cholesterol Granuloma: Report of Two Cases and Review of Literature

Purpose: To report two cases of orbitofrontal cholesterol granuloma, which is a rare progressive destructive disease Case reports: We report two patients with orbitofrontal cholesterol granuloma; a 50-year-old man and a 20-year-old woman; both with progressive proptosis due to a cystic lesion in the superior part of the orbit with frontal bone erosion and intracranial extension. The second case had a previous incomplete surgery 5 years before and presented with recurrent orbital tumor. We performed orbitotomy and cyst evacuation for both cases, which resulted in complete resolution without any complications. At last follow-up (2 and 6 years after operations respectively), no recurrence was observed. Conclusion: We presented the clinical and para-clinical manifestations and surgical results. Complete resolution of symptoms without any recurrence was observed after surgery.