Cyclosporine Effects on Pediatric Kidney Recipients

I read with interest the article by Beiraghdar et al. (1), entitled “Cyclosporine trough and 2 hour post dose monitoring and its contributing factors among pediatric kidney recipients,” recently published in the Nephro- Urology Monthly. The authors correctly mentioned that there is a negative relationship between cyclosporine A levels (C0 and C2) and serum creatinine. Based on their data, the mean of C0 levels (118 ± 65 ng/mL) was in the therapeutic range, which is an acceptable level of cyclosporine after 6 months using the EMIT (Enzyme multiplied immunoassay technique) assay method (2).