Prevention and Treatment of CKD-MBD

Premature arterial ageing has been widely investigated because of its great impact on the general population and especially in chronic kidney disease (CKD) patients. Accelerated atherosclerosis and vascular calcification (VC) is the main histological manifestations of arterial ageing, characterized by cellular necrosis, inflammation, and lipid deposition (1). Differences between VC in general population and CKD patients are not only related to the type and localization of lesions, but also to the early age at which VC lesions begin in CKD patients (2).