Title of article
IS PEPTIC ULCER WITH HELICOBACTER INFECTION THE CAUSE OF CHRONIC URTICARIA?
Author/Authors
Farhoudi, A Department of Immunology and Allergy - Children s Medical Center - Tehran University of Medical Sciences, Tehran , Bazargan, N Department of Immunology and Allergy - Children s Medical Center - Tehran University of Medical Sciences, Tehran , Pourpak, Z Department of Immunology and Allergy - Children s Medical Center - Tehran University of Medical Sciences, Tehran , Movahedi, M Department of Immunology and Allergy - Children s Medical Center - Tehran University of Medical Sciences, Tehran , Moin, M Department of Immunology and Allergy - Children s Medical Center - Tehran University of Medical Sciences, Tehran
Pages
3
From page
17
To page
19
Abstract
Helicobacter pylori, the most important cause of gastritis and peptic ulcer, has recently been associated with several extradigestive diseases. The aim of this study was to assess the prevalence of Helicobacter pylori infection and effects of bacterium eradication in 50 patients affected by idiopathic chronic urticaria. Helicobacter pylori was assessed by serology or biopsy and urease test or !3C urea breath test. Amoxicillin, bismuth subcitrate (Denol), metronidazole and cimetidine were given to infected patients for 2 weeks. The results of therapy were assessed by urea breath test six weeks after therapy. In response to treatment urticaria clinically regressed in 16 out of 24 patients (66.6%). Thus bacterium eradication was associated with a remission of urticaria symptoms, suggesting a possible role in the pathogenesis of this disorder.
Keywords
HELICOBACTER , Denol , Amoxicillin
Journal title
Astroparticle Physics
Serial Year
2000
Record number
2434479
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